
Mulberry Leaf Chlorophyll: A Biohacking Alternative to Methylene Blue and Phytocyanin for Those with Autoimmune Disease?
Looking at Mulberry Leaf Chlorophyll: A Biohacking Alternative to Methylene Blue and Phycocyanin for Those with Autoimmune Disease?
In the ever-evolving world of biohacking, enthusiasts are continually seeking options to improve cellular health, combat oxidative stress, and support overall well-being. Methylene blue (MB) and phycocyanin have gained popularity for their health benefits, but these compounds come with specific concerns—particularly for individuals with autoimmune conditions. Recent research and insights suggest that chlorophyll, particularly from mulberry leaf, may be a viable alternative, providing similar benefits while addressing these concerns.
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A Recent Study on Methylene Blue: Fear or Real Concern?
A recent article references a striking study in Forensic Science, Medicine and Pathology titled, “Fifty shades of green and blue: autopsy findings after administration of xenobiotics.” The study highlights cases where systemic administration of methylene blue resulted in a pronounced blue-green discoloration of vital organs, notably the brain and heart. While this might sound alarming, it’s worth noting that this discoloration, often associated with MB, is primarily a cosmetic effect rather than an indicator of toxicity. Methylene blue’s staining properties are well-documented, and for those using it therapeutically under medical guidance—such as cancer treatments—this may simply be an acceptable trade-off.
Still, the decision to use MB should be carefully weighed. For individuals exploring its use outside of critical medical treatments, organ staining might serve as an unnecessary deterrent, especially when safer alternatives are available.

What is Methylene Blue and Its Common Applications?
Methylene blue (MB) is a synthetic compound initially developed as a textile dye but has since found diverse uses in medicine and research. It is best known for its ability to interact with cellular structures and functions, giving it a wide range of applications, including:
- Medical Uses:
- Antioxidant and Mitochondrial Support: MB enhances mitochondrial function, making it a popular choice for biohackers seeking to optimize energy production at the cellular level.
- Treatment of Methemoglobinemia: MB is used to treat this condition, where hemoglobin cannot efficiently release oxygen to tissues.
- Anti-Microbial Agent: It demonstrates antibacterial and antifungal properties and has been explored for its potential role in fighting infections.
- Emerging Research:
- MB is being studied for its potential in neurodegenerative diseases like Alzheimer’s and Parkinson’s due to its ability to reduce oxidative stress and support brain health.
- Cancer Therapy: Research suggests MB may enhance certain cancer treatments, contributing to its growing appeal in experimental therapies.
Its diverse applications make MB a fascinating compound, but its potential risks—such as the organ staining mentioned earlier—warrant careful consideration and professional guidance.
Is Methylene Blue Safe for Those with Autoimmunity?
Methylene blue (MB) is a fascinating compound with a range of therapeutic applications, but its safety for individuals with autoimmune conditions requires careful consideration. While MB is known for its antioxidant properties and ability to enhance mitochondrial function, it also has immune-modulating effects that could be a double-edged sword for those with autoimmunity.
Potential Concerns:
- Immune Modulation: MB has been shown to influence inflammatory pathways, including reducing neuroinflammation. However, its impact on the immune system is not fully understood, and there is a possibility that it could either calm or exacerbate autoimmune activity, depending on the individual.
- Oxidative Stress and Mitochondrial Function: By improving mitochondrial efficiency and reducing oxidative stress, MB may indirectly benefit autoimmune conditions. However, these effects are highly individual and may vary based on the underlying autoimmune disorder.
- Interactions with Medications: MB can interact with certain medications, such as selective serotonin reuptake inhibitors (SSRIs), and may not be suitable for individuals taking immunosuppressive drugs commonly prescribed for autoimmune conditions.
What to Consider:
- Consult a Healthcare Provider: If you have an autoimmune condition, it’s essential to discuss MB use with your healthcare provider to weigh the potential benefits and risks.
- Start Low and Monitor: If MB is deemed appropriate, starting with a low dose and closely monitoring your symptoms can help identify any adverse effects.
- Personalized Approach: Autoimmune conditions vary widely, and what works for one person may not work for another. A tailored approach is key.
While MB holds promise for many health applications, its use in individuals with autoimmunity should be approached with caution. Always prioritize professional guidance to ensure it aligns with your unique health needs.
What is Phycocyanin and Its Common Uses?
Phycocyanin is a natural pigment-protein complex derived from blue-green algae such as spirulina. It is responsible for the vibrant blue color of the algae and is known for its potent health benefits. Common applications include:
- Health and Wellness:
- Antioxidant Power: It combats oxidative stress, protecting cells from damage caused by free radicals.
- Anti-Inflammatory Benefits: Phycocyanin is believed to reduce inflammation, making it appealing for those managing chronic inflammatory conditions.
- Immune Support: It stimulates the immune system, aiding in the body’s defense mechanisms.*
- Functional and Nutritional Applications:
- Dietary Supplements: Often included in spirulina-based supplements to boost nutritional profiles.
- Natural Food Coloring: Used as a safe, plant-based alternative to artificial blue dyes.
- Experimental Therapies: Research is exploring its role in promoting cellular health and combating diseases like cancer.
*While phycocyanin has a wide array of benefits, its immune-stimulating properties may not be suitable for individuals with autoimmune disorders, requiring gentler alternative options like mulberry leaf chlorophyll.

Why Not Phycocyanin?
For those with autoimmune conditions, phycocyanin’s potential immune-stimulating effects can pose challenges. Overactive stimulation of the immune system can exacerbate symptoms of autoimmune disorders, leading to flare-ups or worsening of the condition.
Signs of an overstimulated immune system can include:
- Increased inflammation, resulting in joint pain or swelling.
- Fatigue that worsens rather than improves with rest.
- Frequent flare-ups of autoimmune symptoms.
- Digestive disturbances or bloating.
- New or worsening skin rashes.
For individuals managing autoimmunity, the goal is often to strike a balance—enhancing cellular health and detoxification without tipping the immune system into overdrive. This is where mulberry leaf chlorophyll might fit in as a promising alternative.
Mulberry Leaf Chlorophyll: A Gentle Yet Effective Option
Chlorophyll, the green pigment responsible for photosynthesis, is abundant in mulberry leaves. When extracted and used as a supplement, it offers several biohacking benefits:
- Cancer-Fighting Potential: Chlorophyll is known for its ability to bind to carcinogens, reducing their absorption and supporting the body’s natural detoxification pathways. This property parallels some of the cancer-related benefits attributed to MB and phycocyanin.
- Antioxidant and Cellular Health: Chlorophyll enhances oxygen transport in the blood and reduces oxidative stress, which can contribute to improved mitochondrial function and energy production—key goals in biohacking.
- Detoxification Support: Chlorophyll aids liver function and facilitates the removal of toxins, including heavy metals, without the risk of organ staining or overstimulation of the immune system.
- Safer for Autoimmunity: Unlike methylene blue and phycocyanin, chlorophyll is less likely to trigger immune system overactivity. Its gentler profile makes it a potentially safer option for those with autoimmune concerns.
How to Use Mulberry Leaf Chlorophyll: A Biohacking Alternative to Methylene Blue and Phytocyanin
Mulberry leaf chlorophyll can be incorporated into your routine in several ways, depending on your preferences and health goals:
- Liquid Drops: Add a few drops of liquid chlorophyll to water, tea, or smoothies. This is one of the most convenient ways to consume it daily.
- Capsules or Tablets: For those who prefer a no-fuss option, capsules or tablets provide a pre-measured dose.
- Powder Form: Mix chlorophyll powder into beverages, soups, or even salad dressings for a nutrient boost.
Always follow the dosage instructions provided by the manufacturer and consult with your healthcare provider to ensure it aligns with your health needs.

What to Look for in a Chlorophyll Supplement
When choosing a chlorophyll supplement, quality and sourcing are key. Here are some factors to consider:
- Source:
- Opt for chlorophyll derived from mulberry leaves rather than algae, as it may be gentler for those with autoimmune concerns.
- Ensure the product specifies its source to avoid unwanted additives or contaminants.
- Formulation:
- Look for supplements that use non-GMO or organic glycerin to ensure a clean and eco-friendly product.
- Avoid artificial colors, flavors, or preservatives.
- Purity and Testing:
- Choose products that are third-party tested for purity and free from heavy metals or toxins.
- Organic certifications can be an added assurance of quality.
- Packaging:
- Opt for BPA-free and environmentally friendly packaging to minimize exposure to harmful chemicals.
By selecting a high-quality chlorophyll supplement, you can maximize its benefits while ensuring it aligns with your health and sustainability values.
A Refreshing Chlorophyll Option: Liquid Chlorophyll
For those seeking to incorporate chlorophyll into their biohacking routine, Buried Treasure Liquid Chlorophyll offers a convenient and revitalizing solution. This formula is designed to support your health while being easy to use in various ways. Whether you’re new to chlorophyll supplementation or looking to switch things up, this product is worth considering.
Key Features:
- Powerful Ingredients: Includes 100 mg of chlorophyll and 4 mg of copper per serving, promoting cellular health and natural detoxification.
- Versatile and Refreshing: Drink it straight, mix it with cold water, iced tea, or blend it into a smoothie for a revitalizing boost.
- Clean Ingredients: Formulated with purified mountain water, vegetable glycerin, spearmint for freshness, and nisin for natural preservation.
Usage Instructions:
- Recommended Dosage: Adults should take 2 tablespoons daily. Be sure to take with food and avoid consuming on an empty stomach.
- Cautions: Pregnant or nursing women should consult their healthcare provider before use. Keep the product out of reach of children.
If you’re interested in trying this supplement, you can enjoy 25% off through my wellness dispensary on Fullscript. It’s part of an ongoing discount available on all supplements in my dispensary. To claim your discount, simply sign up here:
Fullscript – Samantha Teague’s Dispensary
Balancing Benefits and Risks: Empowering Your Choices
If you’re navigating the options between methylene blue, phycocyanin, and mulberry leaf chlorophyll, it’s essential to consider your unique health goals, existing conditions, and the potential risks of each. Treatments like methylene blue for cancer therapy may be worth the trade-offs, even with the possibility of organ staining. For those exploring less intensive biohacking or cellular health optimization, mulberry leaf chlorophyll offers a middle ground with fewer concerns.
As always, these are personal choices that should empower you to take control of your health. Engaging with your healthcare provider to discuss these options will help tailor the right approach for you.
Final Thoughts on Mulberry Leaf Chlorophyll: A Biohacking Alternative to Methylene Blue and Phytocyanin
The world of biohacking is as exciting as it is complex, filled with emerging research and innovative solutions. Mulberry leaf chlorophyll stands out as a gentle, effective alternative for individuals seeking to enhance their health without overstimulating their immune system or risking potential long-term effects like organ staining. Whether you’re drawn to its detoxifying properties, its potential role in cancer prevention, or its contribution to mitochondrial health, it’s a powerful tool to consider in your wellness arsenal.
Remember, informed decisions are the cornerstone of effective health management. Explore, research, and empower yourself to choose the best path forward.
Sources and Further Reading
Methylene Blue Applications and Risks:
- Forensic Science, Medicine and Pathology study, “Fifty shades of green and blue: autopsy findings after administration of xenobiotics”. (Accessed via reputable journals or university library systems for detailed insights).
- General overview of methylene blue’s uses and mechanisms: National Library of Medicine – Methylene Blue Uses and Properties
Phycocyanin Benefits and Uses:
- Research on phycocyanin’s antioxidant and anti-inflammatory properties: Journal of Applied Phycology – Phycocyanin Insights
Chlorophyll and Its Potential as an Alternative:
- Studies on chlorophyll and cancer prevention: National Cancer Institute – Chlorophyll and Carcinogen Binding
- Benefits of mulberry leaf chlorophyll in detoxification and biohacking: Journal of Nutrition – Mulberry Leaf Health Effects
Choosing and Using Chlorophyll Supplements:
Sustainability considerations in chlorophyll supplements: Environmental Working Group (EWG) – Guide to Sustainable Ingredients
Criteria for high-quality formulations: ConsumerLab – Chlorophyll Supplement Testing